Focus: Computational Modeling
1)Introduction to computational modeling and the cell Action Potential -Properties of action potential -Propagation and spiral waves -Impulse propagation, chemical vs electrical synapse
2) Mathematical flow models in biological tissues -Interstitial flow, Diffusion , Pressure difference, Electrical Potential
3) Control of cell volume and transmembrane potential -Membrane, -Diffusion + Active transport for oxygen, nutrients (energy-> ATP), Aqua-porin and Osmosis, Ion Channel and Nernst potential, Sodium Potassium Pump, Volume Control
4) Action Potential -Phases, Goldman Equation, Model for ion channel switching, HH, Markov Chain, FHN, Cardiac Models -Calcium, -Phenotypes
5) Propagation in Tissue -Eq. Cable, gap junctions, Monodomain, gap junctions, myocyte geometry, cardiac fibers -Bidominio, Arrhythmia with or without obstacle (functional and anatomical), Electrotonic effect, phenotypes -Alternans, restitution curve, cardiac arrhythmias -ECG, EEG signals.
Language:English
Host: Rodrigo Weber dos Santos, Bernardo Martins Rocha, Joventino de Oliveira Campos
Lecturer: Blanca Rodriguez (University of Oxford -UK)
Fernando Otaviano Campos (Kings College London -UK)
Mode of instruction : Science Center, Auditorium 1
Courseload: 15h
Date&Time: Jul 29-Aug 2, 2-5pm
Target audience: undergraduate and graduate students
Spots available: 60
Sustainable Development Goals (SDG): 3, 4 and 9